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McCoy AT, et al

The level of subcutaneous tissue necrosis was assessed using a light microscope and scored on a numerical scale, where code 1 reflects no necrosis and code 4 reflects moderate necrosis

7 Melanocortin 4 receptor agonists 7.1 Setmelanotide Setmelanotide is a melanocortin-4 receptor (MC4R) agonist that is administered subcutaneously once a day (124)